VASCULAR RESPONSES TO A NEWLY DEVELOPED CORONARY STENT (NOBORI) COATED WITH THE BIOABSORBABLE POLYMER, POLYLACTIC ACID AND BIOLIMUS A9

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Randomized Comparison of the Nobori Biolimus A9-Eluting Coronary Stent With the Taxus Liberté Paclitaxel-Eluting Coronary Stent in Patients With Stenosis in Native Coronary Arteries

Bernard Chevalier, MD; Sigmund Silber, MD; Seung-Jung Park, MD, PhD; Eulogio Garcia, MD; Gerhard Schuler, MD, PhD; Harry Suryapranata, MD, PhD; Jacques Koolen, MD, PhD; Karl E. Hauptmann, MD; William Wijns, MD, PhD; Marie-Claude Morice, MD; Didier Carrie, MD, PhD; Gerrit-Anne van Es, PhD; Hirofumi Nagai, PhD; Danny Detiege, MS; Dragica Paunovic, MD; Patrick W. Serruys, MD, PhD; for the NOBORI 1...

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VASCULAR BIOLOGY Original Studies In Vivo Comparison of a Polymer-Free Biolimus A9-Eluting Stent With a Biodegradable Polymer-Based Biolimus A9 Eluting Stent and a Bare Metal Stent in Balloon Denuded and Radiated Hypercholesterolemic Rabbit Iliac Arteries

Objectives: To evaluate the effect of a polymer-free Biolimus A9-eluting stent [BioFreedom (BF)], compared with that of a biodegradable polymer-based Biolimus A9-eluting stent [BioMatrix Flex (BMF)] and a bare metal stent (BMS) in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries. Methods: Rabbits were fed with 1% cholesterol diet (n 5 14) for 14 days, both iliac arteries ...

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Biodegradable polymer Biolimus-eluting stent (Nobori®) for the treatment of coronary artery lesions: review of concept and clinical results

First-generation drug-eluting stents have raised concerns regarding the risk of late and very late stent thrombosis compared with bare metal stents and require prolonged dual antiplatelet therapy. Despite extensive investigations, the physiopathology of these late events remains incompletely understood. Aside from patient- and lesion-related risk factors, stent polymer has been cited as one of ...

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Biolimus-A9 polymer-free coated stent in high bleeding risk patients with acute coronary syndrome: a Leaders Free ACS sub-study

Aims Although a true clinical challenge, high bleeding risk patients with an acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) have never been specifically studied. Leaders Free ACS, a pre-specified Leaders Free sub-study, determined efficacy, and safety of a combination of 1-month dual anti-platelet therapy (DAPT) with implantation of either a polymer-free Bioli...

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Biolimus-eluting biodegradable polymer-coated stent versus durable polymer-coated sirolimus-eluting stent in unselected patients receiving percutaneous coronary intervention (SORT OUT V): a randomised non-inferiority trial.

BACKGROUND Third-generation biodegradable polymer drug-eluting stents might reduce the risk of stent thrombosis compared with first-generation permanent polymer drug-eluting stents. We aimed to further investigate the effects of a biodegradable polymer biolimus-eluting stent compared with a durable polymer-coated sirolimus-eluting stent in a population-based setting. METHODS This randomised, ...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2010

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(10)61812-8